It's a while since I read the book but what I remember is him saying that he personally chooses to use it but the evidence is not strong enough to give a definite recommendation so basically, make your own choice.

In the context of new models showing cell identity drift being a threat to longevity (vs simple cell breakdown over time), controlling “low-level” and chronic infection makes more and more sense.

The book is overall excellent and extremely data driven. I have no idea why a book recommendation, on topic, can get downvoted on HN nowadays.